You need to clean the printer when prints are striped or smeared. How often you need to clean the printer will depend on how heavily the printer is used and the environment in which it is used.
Selecting the source for cleaning pages
Cleaning supplies
Light stripes on prints
Cleaning for oily streaks
Cleaning for ink smears: internal paper path
Cleaning for ink smears: paper-feed rollers
Cleaning for ink smears: paper-exit path
Cleaning for media tray jams
Cleaning for lower tray jams: paper-feed rollers